Drug resistance continues to be the principal limiting factor to achieving cures in patients with cancer. The problem of drug resistance in cancer has strong similarities to the field of infectious disease, in that both disciplines are challenged by highly proliferating intrinsic or extrinsic invasive cells. As with antimicrobial therapy, the excitement that was brought about by initial successes of early chemotherapeutics was quickly tempered by evidence showing that although tumors went into remission quickly, they adapted and evolved resistance, resulting in disease relapse.
The Resistance Bio Thesis
The Resistance Bio Thesis
The Resistance Bio Thesis
Drug resistance continues to be the principal limiting factor to achieving cures in patients with cancer. The problem of drug resistance in cancer has strong similarities to the field of infectious disease, in that both disciplines are challenged by highly proliferating intrinsic or extrinsic invasive cells. As with antimicrobial therapy, the excitement that was brought about by initial successes of early chemotherapeutics was quickly tempered by evidence showing that although tumors went into remission quickly, they adapted and evolved resistance, resulting in disease relapse.